Stress: From Eustress to Distress
“A marathon, a new baby, a job promotion and a bereavement are all "stress." Which ones are good for you, and when does any of them stop being so?”
The teaching
- Stress as a normal response. The stress response is adaptive in the short term. Eustress is the term for stress that is challenging and manageable, such as training, learning or a stretching project. Distress is stress that overwhelms the person's capacity to cope or recover. The same event can be either, depending on control, support, duration and recovery.
- Allostasis and allostatic load. Allostasis is stability through change: the body's stress systems adapt to demands. Allostatic load is the cumulative wear and tear when those systems are activated too often, too long, or fail to switch off (McEwen, 1998). Protective and damaging effects of stress mediators depend on how long and how often they are activated.
- Perception and control matter. In the caregiver study (Lesson 4.1), those who perceived themselves as more stressed and unable to control events showed more telomere shortening (Epel et al., 2004). Control, predictability and support shape the biological cost of the same load.
- Psychological ageing. In an Ohio cohort of 660 adults over 50, people with more positive self-perceptions of ageing lived about 7.5 years longer on average, after controlling for age, sex, socioeconomic status, loneliness and functional health (Levy et al., 2002). It is one observational cohort and does not prove that changing attitudes changes survival, but it supports taking attitudes to ageing seriously and asking about them.
- Signs of tipping into distress. Persistent poor sleep, irritability, low mood or anxiety, loss of enjoyment, frequent illness, slow recovery from exercise or illness, muscle tension and headaches, digestive change, and reliance on caffeine, alcohol or sugar to cope. These are signals to explore, not diagnoses.
- Resilience skills. Recovery habits (sleep, movement, time outside), boundaries, social connection, breathing and relaxation practices, graded exposure to challenge, and professional support where needed. Teach as menus, not prescriptions.
- When to refer. Persistent low mood, panic, thoughts of self-harm, substance misuse, or symptoms interfering with work or relationships. Coaches must have a clear route to a clinician or crisis support.
Practitioner / Coach translation
Practitioner | Coach |
|---|---|
Screen for depression, anxiety and burnout; treat or refer | Listen, normalise, teach recovery skills, refer when thresholds are met |
Consider medical contributors (thyroid, anaemia, sleep apnoea) | Do not interpret symptoms as medical causes |
Myth vs Reality
All stress is bad, so remove it.
Manageable challenge builds capacity. Harm comes from unrelenting load without recovery and without a sense of control.
Dr Haq’s 30 Seconds
A short personal take from your course director
Recording to come — 20–40 seconds in Dr Haq’s own words. Suggested angle: How you recognise a patient tipping from coping to distress.
A note on the evidence
Allostatic load: established conceptual framework, with measurement approaches varying. Perceived stress and telomeres: observational. Self-perceptions of ageing and survival: observational, single cohort.
Patient Journey — Checkpoint 15
Richard calls work "always on" (Checkpoint 4), drinks wine to "switch off" (Checkpoint 7). Is this eustress or distress? List three signals you would look for before deciding, and one question you would ask first.
How would you apply this lesson to Richard?
Mini case
A client says they thrive on stress but are waking at 4 am and have stopped training because of fatigue. How do you explore this?
Reflect before you move on
When did stress last make you better at something, and when did it stop doing so?
Format: Video · text · stress-load self-check (downloadable) · quiz.
References
- López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell 2013;153:1194–1217; and The hallmarks of aging: an expanding universe. Cell 2023;186:243–278. (As cited in Module 1.)
- Epel ES, Blackburn EH, Lin J, Dhabhar FS, Adler NE, Morrow JD, Cawthon RM. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA 2004;101(49):17312–17315.
- Telomere Research Network. Recommendations for the measurement of telomere length in population studies (precision and measurement error).
- Watson NF, Badr MS, Belenky G, et al. Recommended amount of sleep for a healthy adult: a joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society. J Clin Sleep Med 2015;11:591–592.
- Cappuccio FP, D'Elia L, Strazzullo P, Miller MA. Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies. Sleep 2010;33:585–592.
- McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med 1998;338:171–179.
- Levy BR, Slade MD, Kunkel SR, Kasl SV. Longevity increased by positive self-perceptions of aging. J Pers Soc Psychol 2002;83:261–270.
- Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 2019;48:16–31.
- WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004;363:157–163.
- Joshi P, Islam S, Pais P, et al. Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. JAMA 2007;297:286–294.
- Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management. Lancet Diabetes Endocrinol 2015;3:1004–1016.
- Alshamsi MA, Fatima W, Al Teneiji MT, Srinivasamurthy SK. Vitamin D status among apparently healthy individuals in the UAE: a systematic review. Front Nutr 2025;12:1604819.
- Oppenheim A, Jury CL, Rund D, Vulliamy TJ, Luzzatto L. G6PD Mediterranean accounts for the high prevalence of G6PD deficiency in Kurdish Jews. Hum Genet 1993;91:293–294.
- Kling J. Race-, ethnicity-based clinical guidelines miss the mark: study (report of Siddique S, Digestive Disease Week 2022). MDedge Family Medicine, 27 May 2022.
- Kauff ND, Perez-Segura P, Robson ME, et al. Incidence of non-founder BRCA1 and BRCA2 mutations in high risk Ashkenazi breast and ovarian cancer families. J Med Genet 2002;39:611.
- El-Shanti H, Majeed HA, El-Khateeb M. Familial Mediterranean fever in Arabs. Lancet 2006;367:1016–1024.
- De Sanctis V, Kattamis C, Canatan D, Soliman AT, et al. β-Thalassemia distribution in the Old World: an ancient disease seen from a historical standpoint. Mediterr J Hematol Infect Dis 2017;9(1):e2017018.
- Ojo AO, et al. APOL1 kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2025;108:763–779.
- Emmett E, O'Connell M, et al. South London Stroke Register analysis of ethnic and socioeconomic inequalities in stroke (30-year data). eClinicalMedicine 2026 (as reported by King's College London, July 2026).
- Brooks PJ, et al. The alcohol flushing response: an unrecognized risk factor for esophageal cancer from acetaldehyde exposure. PLoS Med (as reported in press coverage).
- American Diabetes Association guidance lowering the diabetes screening BMI threshold for Asian Americans to 23 (2015), as summarised by diaTribe. Press coverage differs on the exact wording and later changes; confirm the current ADA position before relying on it.
- Leong DP, Teo KK, Rangarajan S, et al. Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study. Lancet 2015;386:266–273.
- Northey JM, Cherbuin N, Pumpa KL, Smee DJ, Rattray B. Exercise interventions for cognitive function in adults older than 50: a systematic review with meta-analysis. Br J Sports Med 2018;52(3):154–160.
- World Health Organization. Guidelines on physical activity and sedentary behaviour. 2020.
Key Points
- Tell people what a number is, what it is not, and what happens next, especially "biological age" results.
- Ask every person about sleep, stress and movement, and keep a record.
- Offer two or three sleep foundations and let the person pick one.
- Look for the signals of distress before deciding that stress is "good."
- Start strength and balance work early, and keep it gradual.
- Always ask the red-flag questions; refer promptly and document it.